A trial among 5,000 women in Zimbabwe, Uganda and South Africa showed that daily HIV prevention regimens don't work to stop the disease. That may be because many of the women involved in the trial didn't take the medications they were assigned. Today's results illustrate how stigma and fear can waylay disease prevention trials.
The trial, nicknamed VOICE, for Vaginal and Oral Interventions to Control the Epidemic, tested HIV prevention strategies from September 2009 to August 2012 — though it had been planned to run longer, the trial was stopped for futility. There seemed to be no benefit, even though similar preventive tools have worked elsewhere.
One way to prevent HIV from spreading in a high-risk setting is called pre-exposure...
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